The article below is a seminar topic researched by Ogadinma Onyekachi Reformer, a 400 level Animal and Environmental Biology student of the University of Port Harcourt majoring in Animal Health and Physiology.
The definition of non-thyroidal illness arises from the fact that thyroid hormones within blood circulation are reduced not due to the malfunction of thyroid organ, but it is manifested from disorders of other organs. Clinical conditions such as cardiovascular diseases mainly myocardial infraction, sepsis, surgery and many other chronic and sever diseases are associated with thyroid hormones reduction. Serum T3 concentration is reduced during non-thyroidal illness, but serum T4 concentration is seemed to be raised in most of the cases, which is due to the inhibition of T4 conversion into T3 as result of reduced activity of deiodoniase enzyme. It seems the reduction in the T3 concentration does exhibit neither any negative side effect in metabolism nor any irreversible harm in patient involved. There is not any suggestion that hypothyroidism originated from non-thyroidal illness can rapidly lead to fatal outcome but such low reduction in thyroid hormones and particularly T3 can be considered as a key factor for initiating the medical attendance and the necessary steps to prevent further clinical complication.
Researcher: Ogadinma, Onyekachi Reformer
Contact: Email - Reformerogadinma@gmail.com
Phone - 08100682609
Facebook - https://m.facebook.com/ogadinma.reformeronyekachi
DOWNLOAD FULL RESEARCH WORK IN PDF (1.40MB)
DOWNLOAD FULL RESEARCH WORK IN DOC (105KB)
DOWNLOAD SEMINAR PRESENTATION SLIDE IN PPTX (127KB)
ABSTRACT
The definition of non-thyroidal illness arises from the fact that thyroid hormones within blood circulation are reduced not due to the malfunction of thyroid organ, but it is manifested from disorders of other organs. Clinical conditions such as cardiovascular diseases mainly myocardial infraction, sepsis, surgery and many other chronic and sever diseases are associated with thyroid hormones reduction. Serum T3 concentration is reduced during non-thyroidal illness, but serum T4 concentration is seemed to be raised in most of the cases, which is due to the inhibition of T4 conversion into T3 as result of reduced activity of deiodoniase enzyme. It seems the reduction in the T3 concentration does exhibit neither any negative side effect in metabolism nor any irreversible harm in patient involved. There is not any suggestion that hypothyroidism originated from non-thyroidal illness can rapidly lead to fatal outcome but such low reduction in thyroid hormones and particularly T3 can be considered as a key factor for initiating the medical attendance and the necessary steps to prevent further clinical complication.
Researcher: Ogadinma, Onyekachi Reformer
Contact: Email - Reformerogadinma@gmail.com
Phone - 08100682609
Facebook - https://m.facebook.com/ogadinma.reformeronyekachi
DOWNLOAD FULL RESEARCH WORK IN PDF (1.40MB)
DOWNLOAD FULL RESEARCH WORK IN DOC (105KB)
DOWNLOAD SEMINAR PRESENTATION SLIDE IN PPTX (127KB)
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